Cardiovascular biomechanics

Dong Qiu

I study transcatheter heart valves, cardiovascular tissue mechanics, and flow-structure interaction using computational models and benchtop experiments.

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Supplementary File 2 video from Subclinical Leaflet Thrombosis in Supra-annular Transcatheter Aortic Valves.

Valve simulationLeaflet geometry, stress, flow, and thrombosis risk.

Device mechanicsDeployment, underexpansion, and valve-in-valve interactions.

Tissue testingBiaxial mechanics, optical measurement, and validation data.

In-vitro assessmentBenchtop experiments connecting models to valve performance.

Figure from Journal of Biomechanics pinwheeling index paper — Pinwheeling Index
Geometric modeling used to study leaflet degeneration markers in transcatheter valves.

Figure from bicuspid TAVR deployment paper — Bicuspid TAVR
Valve deployment models for eccentric and incomplete stent expansion.

Figure from Frontiers local mechanical characterization article — Local Tissue Mechanics
Optical measurement concepts for local mechanical characterization of cardiovascular tissues.

Figure from leaflet thrombosis flow field paper — Leaflet Flow Fields
Flow-field patterns connecting leaflet design to thrombosis risk.

Current Research Thread

How does leaflet design influence subclinical leaflet thrombosis?

When does valve deployment change stress, flow, and durability?

How can testing data improve patient-specific simulations?

Profile

Postdoctoral researcher in cardiovascular biomechanics work spanning valve simulation, tissue mechanics, and in-vitro validation.

Dong Qiu

Pinwheeling Index

Bicuspid TAVR

Local Tissue Mechanics

Leaflet Flow Fields

Current Research Thread

Profile